abstract：OBJECTIVE:To determine how often unnecessary resting echocardiograms that are "not recommended" by clinical practice guidelines are performed in patients with stable chest pain and normal resting electrocardiograms (ECGs). PATIENTS AND METHODS:We performed a retrospective search of electronic medical records of all ou...

journal_title：Mayo Clinic proceedings

authors： Gibbons RJ,Carryer D,Liu H,Brady PA,Askew JW,Hodge D,Ammash N,Ebbert JO,Roger VL

更新日期：2015-11-01 00:00:00

abstract：OBJECTIVE:To determine the separate effects of exercise intensity and amount on interindividual cardiorespiratory fitness (CRF) response. PARTICIPANTS AND METHODS:Participants were 121 (75 females, 62%) sedentary, middle-aged (mean [SD] age, 53.2 [7.5] years), abdominally obese adults who completed at least 90% of 5 w...

journal_title：Mayo Clinic proceedings

authors： Ross R,de Lannoy L,Stotz PJ

更新日期：2015-11-01 00:00:00

abstract：:The positive relationship between the volume of health services (hospital and physician) and health-related outcomes is established in the complex surgical treatment of cancers and certain nononcologic medical conditions. However, this topic has not been systematically explored in the medical management of cancers. We...

journal_title：Mayo Clinic proceedings

authors： Go RS,Bottner WA,Gertz MA

更新日期：2015-10-01 00:00:00

abstract：OBJECTIVE:To understand motivations, educational needs, and concerns of individuals contemplating whole-exome sequencing (WES) and determine what amount of genetic information might be obtained by sequencing a generally healthy cohort so as to more effectively counsel future patients. PATIENTS AND METHODS:From 2012 to...

journal_title：Mayo Clinic proceedings

authors： Lindor NM,Schahl KA,Johnson KJ,Hunt KS,Mensink KA,Wieben ED,Klee E,Black JL,Highsmith WE Jr,Thibodeau SN,Ferber MJ,Aypar U,Ji Y,Graham RP,Fiksdal AS,Sarangi V,Ormond KE,Riegert-Johnson DL,McAllister TM,Farrugia G,

更新日期：2015-10-01 00:00:00

abstract：OBJECTIVES:To describe cerebrospinal fluid (CSF) findings in patients with posterior reversible encephalopathy syndrome (PRES) and to study its association with vasogenic edema. PATIENTS AND METHODS:Retrospective review of 73 consecutive prospectively collected adults diagnosed with PRES from January 1, 2000, through ...

journal_title：Mayo Clinic proceedings

authors： Datar S,Singh TD,Fugate JE,Mandrekar J,Rabinstein AA,Hocker S

更新日期：2015-10-01 00:00:00

abstract：OBJECTIVE:To evaluate the frequency and appropriateness of nil per os (nothing by mouth) (NPO) orders and determine the number of meals missed because of these orders among hospitalized patients. PATIENTS AND METHODS:We retrospectively analyzed inpatient NPO orders at an academic institution in the United States. The ...

journal_title：Mayo Clinic proceedings

authors： Sorita A,Thongprayoon C,Ahmed A,Bates RE,Ratelle JT,Rieck KM,Devalapalli AP,Issa M,Shah RM,Lalama MA,Wang Z,Murad MH,Kashiwagi DT

更新日期：2015-09-01 00:00:00

abstract：OBJECTIVE:To determine whether women who had a hypertensive pregnancy disorder (HPD) have elevated uric acid concentrations decades after pregnancy as compared with women who had normotensive pregnancies. PATIENTS AND METHODS:The Genetic Epidemiology Network of Arteriopathy study measured uric acid concentrations in H...

journal_title：Mayo Clinic proceedings

authors： Weissgerber TL,Milic NM,Turner ST,Asad RA,Mosley TH Jr,Kardia SL,Hanis CL,Garovic VD

更新日期：2015-09-01 00:00:00

abstract：:Emerging preclinical and clinic evidence described herein suggests that the mechanism of action of rifaximin is not restricted to direct antibacterial effects within the gastrointestinal tract. Data from this study were derived from general and clinical trial-specific PubMed searches of English-language articles on ri...

journal_title：Mayo Clinic proceedings

authors： DuPont HL

更新日期：2015-08-01 00:00:00

abstract：:Drugs that target G protein-coupled receptors (GPCRs) represent the primary treatment strategy for patients with acute and chronic pain; however, there is substantial individual variability in both the efficacy and adverse effects associated with these drugs. Variability in drug responses is due, in part, to individua...

journal_title：Mayo Clinic proceedings

authors： Oladosu FA,Maixner W,Nackley AG

更新日期：2015-08-01 00:00:00

abstract：OBJECTIVE:To examine patterns of the incidence of diabetes, hypertension, and mortality by single units of body mass index (BMI) and 5-year age groups using longitudinal data from middle-aged and older women. PATIENTS AND METHODS:Middle-aged (born between 1946 and 1951; N = 13,715) and older (born between 1921 and 192...

journal_title：Mayo Clinic proceedings

authors： Peeters GM,Herber-Gast GC,Dobson AJ,Brown WJ

更新日期：2015-07-01 00:00:00

abstract：OBJECTIVE:To verify whether absolute monocyte count (AMC) and lymphocyte- monocyte ratio (LMR) at diagnosis are valid prognostic parameters in classical Hodgkin lymphoma (cHL). PATIENTS AND METHODS:Data were collected from 1450 patients with cHL treated in Israel and Italy from January 1, 1988, through December 31, 20...

journal_title：Mayo Clinic proceedings

authors： Tadmor T,Bari A,Marcheselli L,Sacchi S,Aviv A,Baldini L,Gobbi PG,Pozzi S,Ferri P,Cox MC,Cascavilla N,Iannitto E,Federico M,Polliack A

更新日期：2015-06-01 00:00:00

abstract：:Fibromyalgia is the currently preferred term for widespread musculoskeletal pain, typically accompanied by other symptoms such as fatigue, memory problems, and sleep and mood disturbances, for which no alternative cause can be identified. Earlier there was some doubt about whether there was an "organic basis" for thes...

journal_title：Mayo Clinic proceedings

authors： Clauw DJ

更新日期：2015-05-01 00:00:00

abstract：:Data from animal experiments and human studies implicate added sugars (eg, sucrose and high-fructose corn syrup) in the development of diabetes mellitus and related metabolic derangements that raise cardiovascular (CV) risk. Added fructose in particular (eg, as a constituent of added sucrose or as the main component o...

journal_title：Mayo Clinic proceedings

authors： DiNicolantonio JJ,O'Keefe JH,Lucan SC

更新日期：2015-03-01 00:00:00

abstract：OBJECTIVE:To determine whether blood type affects the risk of thromboembolic complications in patients with atrial fibrillation (AF). PATIENTS AND METHODS:The Mayo Clinic electronic medical record was searched (between January 1, 2004, and December 31, 2010) to identify all patients with AF with blood group assessment...

journal_title：Mayo Clinic proceedings

authors： Blustin JM,McBane RD,Mazur M,Ammash N,Sochor O,Grill DE,Wysokinski WE

更新日期：2015-02-01 00:00:00

abstract：OBJECTIVE:To evaluate the long-term prognostic effect of resting heart rate (HR) at index myocardial infarction (MI) and during the first year after MI among 1-year survivors. PATIENTS AND METHODS:The community-based cohort consisted of 1571 patients hospitalized with an incident MI from January 1, 1983, through Decem...

journal_title：Mayo Clinic proceedings

authors： Jabre P,Roger VL,Weston SA,Adnet F,Jiang R,Vivien B,Empana JP,Jouven X

更新日期：2014-12-01 00:00:00

abstract：OBJECTIVE:To analyze a large cohort of patients who underwent exercise testing and also report sex differences in other exercise heart rate (HR) parameters to determine whether separate sex-based equations to predict peak HR are indicated. PATIENTS AND METHODS:Patients aged 40 to 89 years who performed treadmill exerc...

journal_title：Mayo Clinic proceedings

authors： Sydó N,Abdelmoneim SS,Mulvagh SL,Merkely B,Gulati M,Allison TG

更新日期：2014-12-01 00:00:00

abstract：:Brugada syndrome (BrS) is a common occult cause of sudden cardiac arrest in otherwise healthy-appearing adults. The pathognomonic electrocardiographic pattern may be unmasked only by certain medications, many of which are unknown. We report a case of a depressed but otherwise healthy man with an asymptomatic right bun...

journal_title：Mayo Clinic proceedings

authors： Alampay MM,Haigney MC,Flanagan MC,Perito RM,Love KM,Grammer GG

更新日期：2014-11-01 00:00:00

abstract：:The prevalence of skin and soft tissue infections (SSTIs) has been increasing in the United States. These infections are associated with an increase in hospital admissions. Hospitalists play an increasingly important role in the management of these infections and need to use hospital resources efficiently and effectiv...

journal_title：Mayo Clinic proceedings

authors： Amin AN,Cerceo EA,Deitelzweig SB,Pile JC,Rosenberg DJ,Sherman BM

更新日期：2014-10-01 00:00:00

abstract：OBJECTIVE:To describe clinical and laboratory findings from the 2012 southeastern Minnesota pertussis outbreak. PATIENTS AND METHODS:Patients were selected for 2 parts of the study. In the first part, nasopharyngeal swabs from a convenience sample of 265 unique patients were used for both the clinician-requested polym...

journal_title：Mayo Clinic proceedings

authors： Theofiles AG,Cunningham SA,Chia N,Jeraldo PR,Quest DJ,Mandrekar JN,Patel R

更新日期：2014-10-01 00:00:00

abstract：OBJECTIVE:To evaluate the association of coronary artery calcium (CAC) and coronary heart disease (CHD) events among young and elderly individuals. PARTICIPANTS AND METHODS:This is a secondary analysis of data from a prospective, multiethnic, population-based cohort study designed to study subclinical atherosclerosis....

journal_title：Mayo Clinic proceedings

authors： Tota-Maharaj R,Blaha MJ,Blankstein R,Silverman MG,Eng J,Shaw LJ,Blumenthal RS,Budoff MJ,Nasir K

更新日期：2014-10-01 00:00:00

abstract：OBJECTIVE:To investigate a recent association between the use of the angiotensin receptor-blocker (ARB) olmesartan and a severe enteropathy resembling celiac disease. PATIENTS AND METHODS:We searched our endoscopy database for all outpatient esophagogastroduodenoscopy (EGD) or colonoscopy examinations in patients aged...

journal_title：Mayo Clinic proceedings

authors： Greywoode R,Braunstein ED,Arguelles-Grande C,Green PH,Lebwohl B

更新日期：2014-09-01 00:00:00

abstract：:Iatrogenic injury-injury caused unintentionally by medical treatment-breaks the oldest and most famous rule of medical ethics: primum non nocere, or above all, do no harm. Medical malpractice law, however, focuses on whether an injury was caused by negligence, not on whether an injury was iatrogenic. Iatrogenic injury...

journal_title：Mayo Clinic proceedings

authors： Klaas PB,Berge KH,Klaas KM,Klaas JP,Larson AN

更新日期：2014-09-01 00:00:00

abstract：OBJECTIVE:To determine the association between cardiorespiratory fitness and sedentary behavior, independent of exercise activity. PATIENTS AND METHODS:We included 2223 participants (aged 12-49 years; 1053 females [47%]) without known heart disease who had both cardiovascular fitness testing and at least 1 day of acce...

journal_title：Mayo Clinic proceedings

authors： Kulinski JP,Khera A,Ayers CR,Das SR,de Lemos JA,Blair SN,Berry JD

更新日期：2014-08-01 00:00:00

abstract：OBJECTIVE:To investigate the incidence of bone disorders after solid organ transplantation (SOT). PARTICIPANTS AND METHODS:We used Taiwan's National Health Insurance Research Database to identify 9428 recipients of SOT and 38,140 sex- and age- matched control subjects between January 1, 1997, and December 31, 2010, to...

journal_title：Mayo Clinic proceedings

authors： Yu TM,Lin CL,Chang SN,Sung FC,Huang ST,Kao CH

更新日期：2014-07-01 00:00:00

abstract：OBJECTIVE:To determine how all-cause hospitalizations within 12 months preceding an index heart failure (HF) hospitalization affect risk stratification for 30-day all-cause readmission. PATIENTS AND METHODS:Early readmission of inpatients with HF is challenging to predict, yet this outcome is used to compare hospital ...

journal_title：Mayo Clinic proceedings

authors： Hummel SL,Katrapati P,Gillespie BW,Defranco AC,Koelling TM

更新日期：2014-05-01 00:00:00

abstract：OBJECTIVE:To assess the frequency and clinical implications of positive autoimmune serologies in patients with biopsy-confirmed idiopathic pulmonary fibrosis (IPF). PATIENTS AND METHODS:We reviewed the records of patients at our institution with biopsy-confirmed usual interstitial pneumonia (UIP) from January 1, 1995,...

journal_title：Mayo Clinic proceedings

authors： Moua T,Maldonado F,Decker PA,Daniels CE,Ryu JH

更新日期：2014-03-01 00:00:00

abstract：OBJECTIVE:To investigate whether patients with traumatic brain injury (TBI) have an increased risk of stroke or poststroke mortality. PARTICIPANTS AND METHODS:Using Taiwan's National Health Insurance Research Database, we conducted a retrospective cohort study of 30,165 patients with new TBI and 120,660 persons withou...

journal_title：Mayo Clinic proceedings

authors： Liao CC,Chou YC,Yeh CC,Hu CJ,Chiu WT,Chen TL

更新日期：2014-02-01 00:00:00

abstract：OBJECTIVE:To explore the current epidemiological profile of Marfan syndrome in a general population. PATIENTS AND METHODS:Patients who had received a diagnosis of Marfan syndrome were identified from the Taiwan National Health Insurance database records from January 1, 2000, through December 31, 2012 (average populati...

journal_title：Mayo Clinic proceedings

authors： Chiu HH,Wu MH,Chen HC,Kao FY,Huang SK

更新日期：2014-01-01 00:00:00

abstract：UNLABELLED:Cirrhosis and liver cancer, the main causes of liver-related morbidity and mortality, result from defective repair of liver injury. This article summarizes rapidly evolving knowledge about liver myofibroblasts and progenitors, the 2 key cell types that interact to orchestrate effective repair, because deregu...

journal_title：Mayo Clinic proceedings

authors： Machado MV,Diehl AM

更新日期：2014-01-01 00:00:00

abstract：OBJECTIVE:To examine 45-year trends in time use and physical activity energy expenditure (PAEE) in a nationally representative sample of US mothers. PARTICIPANTS AND METHODS:We quantified time allocation to physical activity (PA), sedentary behaviors (SED), and PAEE from 1965 to 2010 in mothers with older children (MO...

journal_title：Mayo Clinic proceedings

authors： Archer E,Lavie CJ,McDonald SM,Thomas DM,Hébert JR,Taverno Ross SE,McIver KL,Malina RM,Blair SN

更新日期：2013-12-01 00:00:00

abstract：:In Olmsted County, Minnesota, population-based epidemiologic research studies are possible because of a unique medical records linkage system, the Rochester Epidemiology Project (REP), which has been in place for almost half a century. We present a summary of epidemiologic data describing the incidence of skin disease...

journal_title：Mayo Clinic proceedings

authors： Andersen LK,Davis MD

更新日期：2013-12-01 00:00:00

abstract：OBJECTIVE:To verify preliminary studies on patients with melanoma exposed to β-blockers that suggested a reduced risk of disease recurrence and death. PATIENTS AND METHODS:Data were obtained from all consecutive patients diagnosed as having melanoma between January 1, 1993, and December 31, 2009, at the Department of ...

journal_title：Mayo Clinic proceedings

authors： De Giorgi V,Gandini S,Grazzini M,Benemei S,Marchionni N,Geppetti P

更新日期：2013-11-01 00:00:00

abstract：OBJECTIVE:To evaluate the association between coffee consumption and mortality from all causes and from cardiovascular disease. PATIENTS AND METHODS:Data from the Aerobics Center Longitudinal Study representing 43,727 participants with 699,632 person-years of follow-up were included. Baseline data were collected by an...

journal_title：Mayo Clinic proceedings

authors： Liu J,Sui X,Lavie CJ,Hebert JR,Earnest CP,Zhang J,Blair SN

更新日期：2013-10-01 00:00:00

abstract：:Clinical decisions are increasingly driven by evidence-based recommendations of guideline groups, which aim to be based on the highest quality knowledge-randomized clinical trials (RCTs) and meta-analyses. Although RCTs provide the best assessment of the overall value of a therapy, high-quality evidence from RCTs is o...

journal_title：Mayo Clinic proceedings

authors： Sniderman AD,LaChapelle KJ,Rachon NA,Furberg CD

更新日期：2013-10-01 00:00:00

abstract：:Restless legs syndrome (RLS)/Willis-Ekbom disease (WED) is a common disorder, occurring at least twice a week and causing at least moderate distress in 1.5% to 2.7% of the population. It is important for primary care physicians to be familiar with this disorder and its management. Much has changed in its management si...

journal_title：Mayo Clinic proceedings

authors： Silber MH,Becker PM,Earley C,Garcia-Borreguero D,Ondo WG,Medical Advisory Board of the Willis-Ekbom Disease Foundation.

更新日期：2013-09-01 00:00:00

abstract：:Ulcerative colitis diagnosis and management represent a challenge for clinicians. The disguises of ischemia and acute infectious colitis continue to confound the diagnosis. The therapeutic options have remarkably expanded in the way of immunomodulators, biologics, or ileoanal pouch surgery, yet all carry potential con...

journal_title：Mayo Clinic proceedings

authors： Katz S

更新日期：2013-08-01 00:00:00

abstract：OBJECTIVE:To identify medical practices that offer no net benefits. METHODS:We reviewed all original articles published in 10 years (2001-2010) in one high-impact journal. Articles were classified on the basis of whether they addressed a medical practice, whether they tested a new or existing therapy, and whether resu...

journal_title：Mayo Clinic proceedings

authors： Prasad V,Vandross A,Toomey C,Cheung M,Rho J,Quinn S,Chacko SJ,Borkar D,Gall V,Selvaraj S,Ho N,Cifu A

更新日期：2013-08-01 00:00:00

abstract：OBJECTIVE:To evaluate the effect of aspirin and nonaspirin antiplatelet agents (NAAAs) on the performance of the fecal immunochemical test (FIT). PARTICIPANTS AND METHODS:We performed a post hoc analysis of results from a clinical trial that involved 28,696 asymptomatic average-risk men and women aged 50 to 69 years i...

journal_title：Mayo Clinic proceedings

authors： Bujanda L,Lanas Á,Quintero E,Castells A,Sarasqueta C,Cubiella J,Hernandez V,Morillas JD,Perez-Fernández T,Salas D,Andreu M,Carballo F,Bessa X,Cosme A,Jover R,COLONPREV Study Investigators.

更新日期：2013-07-01 00:00:00

abstract：:It is now generally accepted that vitamin D deficiency is a worldwide health problem that affects not only musculoskeletal health but also a wide range of acute and chronic diseases. However, there remains cynicism about the lack of randomized controlled trials to support the association studies regarding the nonskele...

journal_title：Mayo Clinic proceedings

authors： Hossein-nezhad A,Holick MF

更新日期：2013-07-01 00:00:00

abstract：:Given the burden of cardiovascular disease (CVD), increasing the prevalence of healthy lifestyle choices is a global imperative. Currently, cardiac rehabilitation programs are a primary way that modifiable risk factors are addressed in the secondary prevention setting after a cardiovascular (CV) event/diagnosis. Even ...

journal_title：Mayo Clinic proceedings

authors： Arena R,Guazzi M,Briggs PD,Cahalin LP,Myers J,Kaminsky LA,Forman DE,Cipriano G Jr,Borghi-Silva A,Babu AS,Lavie CJ

更新日期：2013-06-01 00:00:00